Timed Behaviors in Mice

The mouse has an extensive capacity to modulate timed responses and arm movements according to different environmental conditions and different genetic background may affect this ability. Recently, we have characterized a number of quantitative and qualitative meaningful endophenotypes related to mouse timing mechanisms and different motor actions. We have further investigated timing and motor behaviors in mice by acute experiments and long-term monitoring. Novel technological advances allowed us to simultaneous monitor brain and muscle electrical activity, spontaneous and conditioned behaviors as well as metabolic profiles during 24-hours in testing and home-cage environments. We have used these new technologies to screen for novel mutants and to characterize existing mouse lines.